Prof Kenny K. Chung

PhD University of Cambridge

Associate Professor, Division of Life Science
Representing Faculty, School of Science

Research Interests

Molecular mechanisms of Neurodegeneration. Functional studies of genes that are linked to familial Parkinson’s disease.

Highlighted Publications

Wang, Y., Sung, C.C. and Chung, K.K. (2017). Novel enhancement mechanism of tyrosine hydroxylase enzymatic activity by nitric oxide through S-nitrosylation. Scientific Reports. 7:44154. doi: 10.1038/srep44154.

Wu, W., Wan, O.W. and Chung, K.K. (2015). S-nitrosylation of XIAP at Cys 213 of BIR2 domain impairs XIAP’s anti-caspase 3 activity and anti-apoptotic function. Apoptosis, 20: 491-9.

Wan, O.W. and Chung, K.K. (2012). The role of α-synuclein oligomerization and aggregation in cellular and animal models of of Parkinson’s disease. PLoS ONE. 7(6): e38545.

 Xie, W. and Chung, K.K. (2012). α-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson’s disease. J. Neurochem.122:404-14.

Tsang, A.H., Lee, Y.I., Ko, H.S., Savitt, J. M., Pletnikova, O. Troncoso, J.C., Dawson, V.L., Dawson, T.M. and Chung, K.K. (2009). S-Nitrosylation of XIAP compromises neuronal survival in Parkinson’s disease. Proc Natl Acad Sci U S A. 106: 4900-5.